Venlafaxine (Effexor)

Venlafaxine belongs to a class of antidepressant drugs known as SSRIs, and is used to treat depression, general anxiety disorder (GAD), and seasonal affective disorder (SAD). It works by increasing certain kinds of activity in the brain. In animals, this drug has been shown to be an effective pain reliever. Studies evaluating venlafaxine for pain have shown that this drug may alter pain tolerance thresholds thereby providing a pain-relieving effect in headache or other conditions. Side effects of effexor include upset stomach, drowsiness, weakness, tiredness, excitement, anxiety, difficulty sleeping, nightmares, dry mouth, skin sensitivity to sunlight, changes in appetite or weight, and headache.

Major depressive disorder, generalized anxiety disorder, social anxiety disorder, depression, social phobia.

Also, patients can order venlafaxine online to treat attention deficit/hyperactivity disorder (ADHD), chronic neuropathic pain, diabetic neuropathy, fibromyalgia, menopausal symptoms, migraine prevention, obsessive-compulsive disorder (OCD), panic disorder, premenstrual dysphoric disorder (PMDD), tension headache prevention.

Buspirone, lithium, meperidine, nefazodone, selegiline, serotonin agonists, sibutramine, selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, paroxetine, etc.), trazodone, tricyclic antidepressants, haloperidol, indinavir, phenobarbital, carbamazepine, phenytoin.

Concurrent use of MAO inhibitors or drugs with MAO inhibitor activity may result in serotonin syndrome; should not be used within two weeks of each other.

Alcohol

Valerian, St. John's wort, SAMe, kava kava, tryptophan.

FDA Pregnancy Risk Category C. Excreted in breast milk. Do not use while breast-feeding.

Neonates exposed to venlafaxine late in the third trimester of pregnancy have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding. Such complications can arise immediately upon delivery.

Where can I buy Venlafaxine without prescription?
Venlafaxine antidepressant is a prescription drug that comes in 37.5 mg, 75 mg capsules. It is available on prescription only as capsules for oral use, but the online pharmacy, will sell Effexor without prescription. You may be able to order Effexor from them online and save the local pharmacy markup.

In a study, 170 adults with migraine or chronic tension-type headache were treated with Effexor for six months. Results showed that the mean frequency of tension headaches decreased from 24/month to 15.2/month. Thirty percent of patients with tension-type headache had 50% reduction in headaches and 41% of patients with moderate to severe tension-type headaches had greater than 50% reduction in headaches with the use of this drug.

Adverse drug reactions seen in this study, which led to discontinuing venlafaxine, included nausea, difficulty sleeping, and excessive tiredness and weakness. Researchers concluded that Effexor has potential as a headache prevention drug.

This drug is used to treat mood disorders. It works by inhibiting serotonin and norepinephrine reuptake by brain neurons. This action is helpful in increasing levels of both these neurotransmitters.

Brand name
Effexor, Effexor XR

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Generic name
Venlafaxine

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Chemical class
Phenethylamine derivative

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Therapeutic class
Antidepressant (Serotonin/Norepinephrine Reuptake Inhibitor [SNRI])

Capsules - Oral 37.5 mg, 75 mg.

ADULT
PO starting dose 75 mg/day, given bid or tid; increase daily dose by 75 mg up to 225 mg/day, given bid or tid (375 mg/day for severe depression) at intervals of no less than 4 days.

Reduce total daily dose 25% in patients with mild to moderate renal impairment, by 50% in patients with severe renal impairment; dialysis patients should receive dose after dialysis; reduce total daily dose by 50% in patients with moderate hepatic impairment.

When discontinuing drug, taper over 2 week.